The Lewis lab research interests are focused on the development of radiopharmaceuticals for targeted diagnosis and treatment of cancer. By combining small- and biomolecule-based targeting agents with positron-emitting or therapeutic radioisotopes, we can interrogate molecular profiles of cancer using noninvasive nuclear imaging or treat tumors specifically with endoradiotherapy. Our research program is a molecular-imaging-based program focused on the targeting of nonstandard nuclides, with an emphasis on developing these novel radiopharmaceuticals for clinical translation